Search on: PHOSPHOLIPASES A2, SECRETORY 
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Descriptor English:   Phospholipases A2, Secretory 
Descriptor Spanish:   Fosfolipasas A2 Secretoras 
Descriptor Portuguese:   Fosfolipases A2 Secretórias 
Tree Number:   D08.811.277.352.100.680.750.937.750
Definition English:   A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52667 
Unique Identifier:   D054497 

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